We are this, but I think the jury is still out. Is there any indication that, for example, breakthrough infections would have a different result long term? This study was done before vaccination was widely available. Why would SARS-CoV-2, the virus that causes COVID 19, which we all thought about as a respiratory virus, attack the heart up to a year down the road? That’s likely one of the explanations. That allows the virus into cells, including heart cells. The virus has something called a spike protein, which is like a key that engages a lock-the ACE receptor. There are several other mechanisms that revolve around something called the ACE receptor. Some of these cells might die and eventually facilitate the formation of blood clots and blockages of the arteries or vessels of the heart. It's possible that COVID-19 may attack the endothelial cells that line the vessels of the heart. It's possible that the virus itself and the immune response to it cause an intense inflammation that subsequently hits the heart and results in some of the manifestations we've seen here.
People who got COVID-19 and were asymptomatic, or got COVID-19 that was so mild that they were able to nurse it at home, without going to the doctor still developed an increased risk of heart problems a year out.Ī lot of different things could be happening. It was really eye-opening that the risk was also evident in people who did not have severe COVID-19 that necessitated hospitalization or ICU care. What we found is that even in people who did not have any heart problems start with, were athletic, did not have a high BMI, were not obese, did not smoke, did not have kidney disease or diabetes-even in people who were previously healthy and had no risk factors or problems with the heart-COVID-19 affected them in such a way that manifested the higher risk of heart problems than people who did not get COVID-19. I went into it thinking that was going to be most pronounced and evident in people who smoked a lot or had diabetes, heart disease, kidney disease, or some risk factors.
The increased risk of a broad spectrum of heart problems was evident. We found evidence of an increased risk of stroke, of blood clots in the legs and the lungs, and of heart failure and heart attacks. That included arrhythmias (irregular heart beats or the heart beating too fast or too slow) and atrial fibrillation (a fast heart rhythm in a particular pattern). The major finding was that people with COVID-19 have a higher risk of all sorts of heart problems at one year. We did this study to evaluate the one-year risk of heart problems in people who got COVID-19, compared to nearly 11 million controls of people who did not. We didn't know what happened to people's hearts in the long term-six months to a year out-or what happened to people who had mild disease and did not need hospitalization or ICU care. We've known for a while that during the acute phase-the first 30 days of COVID-19-people who have severe disease and need to be admitted to the hospital or ICU may develop heart complications. What does this mean and what did you study? You just published a study that says that in some people who’ve had COVID, heart issues can persist for a year or more. Louis Health Care System, talks with Stephanie Desmon about COVID-19 and the heart, including his recent study, which found a significant risk of heart problems in people a year after being diagnosed with COVID. In this Q&A, adapted from the March 9 episode of Public Health On Call, Ziyad Al-Aly, director of the Clinical Epidemiology Center and chief of Research and Education Service at Veterans Affairs St. But new evidence has revealed that anyone infected with COVID is at higher risk for heart issues-including clots, inflammation, and arrhythmias-a risk that persists even in relatively healthy people long after the illness has passed. Until now, people who suffered mild or asymptomatic COVID-19 were thought to have dodged the brunt of the virus’s brutal side effects.
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